Antabuse (Disulfiram)

What is Antabuse?

Antabuse is a drug that helps people to stop drinking alcohol. It does this by causing unpleasant side effects if the person drinks while they are taking Antabuse. These side effects include feeling sick, vomiting, and diarrhea.

What is Antabuse used for?

Antabuse is a medication that is used to help treat alcoholism. It blocks the effects of alcohol and can help prevent a relapse. It is not a cure for alcoholism, but it can be an important part of treatment.

What is Antabuse? Ultimately, the drug is effective in treating alcohol use disorder because it combines pharmacological action with psychological conditioning to achieve long-term abstinence or reduced consumption of alcohol. It prevents individuals from being able to drink while still allowing them some degree of autonomy over their actions and choices related to recovery. As such, Antabuse remains one of the most widely used treatments for excessive and problematic drinking behaviors today.

How does it work? (Mechanism of action)

Antabuse, also known as disulfiram, is an FDA-approved medication used to treat alcohol use disorder. It works by blocking the breakdown of alcohol in the body, causing an unpleasant reaction when alcohol is consumed. This reaction includes nausea, vomiting, headache, and flushing. Additionally, the medication increases levels of acetaldehyde in the blood, which further intensifies the unpleasantness of drinking. The effects of Antabuse pills can last up to seventy-two hours after alcohol consumption.

Antabuse works on a psychological level as well. By triggering an aversive response when consuming alcohol, it reinforces negative associations with drinking and encourages individuals to abstain from using it completely or cut down their consumption significantly. Furthermore, just taking the pill encourages commitment and motivation toward recovery from substance abuse without any additional effort required from a patient.

How long does Antabuse stay in your system?

The pharmacokinetics of Antabuse medication are complex and involve multiple steps in order for it to be effective. After ingestion, the substance is quickly absorbed from the gastrointestinal tract and reaches peak plasma concentrations within 1-2 hours. It is then metabolized by the liver into its active form (diethyldithiocarbamate), which binds irreversibly with specific hepatic enzymes responsible for acetaldehyde metabolism. This inhibition leads to the accumulation of acetaldehyde in the blood, which causes an unpleasant reaction when combined with alcohol intake. The metabolites of Antabuse are then slowly eliminated via kidneys over several days or even weeks.

The pills should not be taken without first consulting a medical professional since it could interact with other drugs and cause severe reactions if taken improperly. Furthermore, because Antabuse stays in the body for up to two weeks after stopping use, individuals who wish to drink must wait for at least this long before doing so as they will still experience Antabuse reaction otherwise.

Antabuse generic works by blocking the effects of alcohol in the brain, and this can cause unpleasant side effects. It stays in your system for quite a long time, and it can take up to two weeks for the drug to be cleared from your body.

What are the side effects?

When combined with alcohol, severe side effects of Antabuse can be observed, which is the purpose of using this drug. If a coded drinks alcohol, then he will experience:

  •  Nausea, bitterness in the mouth, vomiting.
  •  Diarrhea, abdominal pain.
  •  A sharp increase or decrease in blood pressure, tachycardia.
  •  Shortness of breath, dizziness, confusion.
  •  Convulsions, tremor of the limbs.
  •  Rash, redness of the skin.

Such reactions should stop a person from drinking alcohol. If the patient, despite all the torment, continues to combine alcohol with the medicine, then a serious threat to life may arise. The combination with the drug of large doses of ethanol is dangerous – when taking doses of pure alcohol over 50–80 ml, severe disorders of the cardiovascular and respiratory systems can develop.


When taking Antabuse, it is important to take certain precautions in order to ensure that the medicine is taken safely. Before starting this medication, it is essential to tell your doctor about any other medications you are currently taking, including vitamins and herbal supplements. Additionally, all other medical conditions should be discussed with your doctor to determine if Antabuse is safe for you. It is also important to let your doctor know if you are pregnant or planning to become pregnant, as the safety of this medication has not been established in pregnant women.

It is critical that the instructions provided by your doctor be followed carefully. This includes the dose and frequency of administration as well as avoiding alcohol or other medicines containing alcohol. If you do drink alcohol while on this medication, a potentially dangerous reaction may occur, which could be life threatening. It is also important that no one else take your medication, as doing so can lead to serious health problems and even death in some cases.

Regular checkups with your physician are advised in order to monitor Antabuse side effects and make sure the medication is working properly. Do not adjust the dose without consulting a doctor first; changing Antabuse dosage or discontinuing use without consulting a physician could cause serious adverse reactions. Additionally, it should never be shared with another person, even if they have similar symptoms, because it may not be safe for them. If there are any questions or concerns while taking this drug, contact a medical professional immediately for advice and care.


Contraindications for taking disulfiram Antabuse should be considered prior to beginning treatment. The drug should not be taken by individuals who may have had an allergic reaction to any of the individual components of the medication in the past. Additionally, individuals with psychiatric conditions, liver disease, and certain blood disorders should avoid taking this medication unless directed by a physician. It is also important to note that pregnant women or those who are breastfeeding should not take this medication as it can cause harm to an unborn or nursing child. Finally, due to potential interactions with other medications, it is essential that all current medications be discussed with a healthcare provider prior to beginning Antabuse therapy. It can be dangerous if used incorrectly and it is important for patients to only take it as prescribed and follow all instructions provided by their healthcare provider. Contraindications for taking this medication should always be weighed carefully before starting any treatment plan involving disulfiram.

What happens if you drink on Antabuse

If you drink on generic Antabuse, you will vomit. The drug makes you sick to your stomach when you drink alcohol because it interferes with the way your body breaks down alcohol. How to drink on Antabuse? When Antabuse and alcohol are taken together, the person may feel very ill and vomit.

Where to buy Antabuse

Antabuse is a prescription medication that is used to treat alcohol dependence. It helps reduce cravings for alcohol and prevents relapse. The cost of Antabuse over the counter will vary depending on the pharmacy you choose, but it is typically quite affordable. When it comes to buying Antabuse, there are a few things you should keep in mind. First, it is important to find a reputable and reliable source. Second, make sure that you are getting a genuine product buying Antabuse online. Finally, be sure to ask your doctor any questions you may have about the medication.